Buffalo's official totals show Allen at 786 passing yards with five touchdowns and Cook at 346 rushing yards on 58 carries. New England entered Week 4 at 1-2 after a 35-6 loss, with Maye at one touchdown against six interceptions through three games. Buffalo has the more stable scoring paths, although divisional familiarity and Maye's rushing ability keep the probability below an extreme tier.
Winner reasoning, risks and sources
UNCALIBRATED subjective research estimate rounded to five points. Buffalo's 3-0 start, Josh Allen's 9.1 yards per attempt and James Cook's explosive workload create a clear home lean, while Drake Maye's mobility preserves meaningful upset variance.
- New England won 23-20 in Buffalo in 2025 despite entering as a substantial underdog.
- Cook and Kincaid production is drawn from only three games.
- Buffalo defensive injuries and New England offensive-line and receiver statuses require official Week 4 review.
- Kickoff wind is not yet resolved for an outdoor Orchard Park game.
Buffalo Bills official 2026 team statistics ↗
Allen was 56-of-86 for 786 yards with five touchdowns and two interceptions; Cook had 346 rushing yards; Kincaid had 263 receiving yards; Shakir had eight catches for 94 yards.
Observed 2026-09-28T15:20:00Z
New England Patriots official 2026 team statistics ↗
Maye was 51-of-80 for 585 yards with one touchdown and six interceptions; Stevenson had 116 rushing yards; New England had 180 team rushing yards at 4.6 per attempt.
Observed 2026-09-28T15:20:00Z
NFL official Drake Maye statistics ↗
Maye had 82 rushing yards on 15 attempts through three games.
Observed 2026-09-28T15:20:00Z
Pats Pulpit display of FanDuel Week 4 prices ↗
The September 28 publisher display showed Buffalo -6.5, Buffalo -330 and a 48.5 total. It was not independently verified as executable.
Observed 2026-09-28T15:20:00Z
New York Post report on A.J. Brown's ankle injury ↗
The report described Brown as out indefinitely with an ankle injury; he is excluded from these outcomes, and Week 4 availability is not otherwise inferred.
Observed 2026-09-28T15:21:00Z
Orchard Park daily weather forecast ↗
The observed kickoff-hour outlook was intermittent clouds near 60F, with temperatures rising into the low-to-mid 60s; wind and precipitation require a later check.
Observed 2026-09-28T15:00:00Z